Fierce Biotech published thumbnails on 15 top late stage drugs that it says analysts have pegged at having a chance to exceed $1 B in peak year sales. Predictably, most of these come from the biggest of Big Pharma and attack some of the reallybig disease classes like breast cancer or Alzheimer's. A drum roll please for our list:
- TDM1 - Genentech - breast cancer - $5 B peak
- BG-12 - Biogen Idec - multiple sclerosis - $3 B peak
- Darapladib - GSK - atherosclerosis - multi-billion peak
- Gantenerumab - Roche/Morphosys - Alzheimer's - TSTL*
- GS-7977 - Gilead - hepatitis C - $3.8 B
- REGN727 - Sanofi/Regeneron - cardiovascular disease - $6 B
- Odanacatib - Merck - osteoporosis - $2.5 B
- Anacetrapib - Merck - cardiovascular disease - $10 B
- Eliquis (apixaban) - BMS/Pfizer - atrial fibrillation - $5 B
- Tofacitinib - Pfizer - rheumatoid arthritis - $3 B
- Bardoxolone - Reata/AbbVie - chronic kidney disease - multi-billions
- LuAA21004/vortioxetine - Lundbeck/Takeda - major depression - $2 B
- QVA149 - Novartis - COPD - $1.5 B
- Macitentan - Achelion - pulmonary arterial hypertension - $3 B
- Alpharadin - Bayer/Algeta - cancer - $1 B
There's the roster. Now you can place your bets -- though I didn't I did neglect to post the remaining odds of success.
Posted by Bruce Lehr Oct 8th 2012.


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