At April's Cell Culture Engineering (CCE) XII Conference, Dr. Bernhard Palsson, the Galetti Professor of Bioengineering at UCSD , and founder of bio companies like Cyntellect and Genomatica, did a talk on "CHO-mics".
CHO-mics involves full genome sequencing of CHO with comparative sequence analysis. The idea is to unravel metobolic pathways and control of processes like glycosylation. During the talk he indicated that his collaborators have looked at 626 metabolites, 709 reactions and 104 glycosylation genes (unpublished).
However, the most interesting statement during the talk was that Dr. Palsson's group was collaborating with the Beijing Genome Institute to sequence CHO. They expected to publish this information after assembly and annotation. It was implied that the work could be completed within the next two years.
Posted by Bruce Lehr May 15th 2010.