Scientists in the SAFC Biosciences Cell Science and Development (CSD) department have pubished a new paper on a novel sialylation gene in CHO, called neu 3. The group confirmed neu 3 functionality by knocking it down with siRNA and shRNA to suppress gene function. They confirmed a model gamma interferon increased in its degree of sialylation under these conditions. This will come out in Biotechnology and Bioengineering. Lead authors for this study were Min Zhang and Scott Ross.
Posted by Bruce Lehr January 31, 2010